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Alopecia Areata: In Brief

Without doubt one of the most unusual and mysterious causes of baldness is Alopecia areata. Although there is little that is entirely typical about this very rare disorder, it is likely to develop at an early age (around 20) and it affects men and women equally. Most regularly, it takes the form of one or more round shaped bald patches appearing on the scalp, which is often remarkably fast developing. One saving grace is that it is not uncommon for these patches regrow after a few months, but in a minority of cases there is complete loss of scalp hair (Alopecia totalis). There is also an even rarer variant, known as Alopecia universalis, which results in total hair loss (including scalp, eyelashes, eyebrows, facial hair and body hair).

What causes this rare and bizarre condition?

It is believed that Alopecia areata, and its variants, are caused by a disorder of the auto-immune system- white blood cells mistake hair follicles for foreign agents or infections and attack them. It is not known why it usually only affects certain areas of the scalp, let alone why the auto-immune system malfunctions in this way in the first place. Some causes are thought to be: infections, viruses, medications or (mostly likely) genetics.

Are there any treatments?

  • One treatment may be steroid treatment or topical application to the affected area. Steroids helps suppress the dysfunctional immune system in the relevant areas, which can allow to hair follicles to recover normal growth. However, injections need to be applied by a specialist, whereas the topical application takes longer to work. Most importantly, they do not work for everyone!
  • Another possible treatment is minoxidil. Anybody who is familiar with the medication- or anyone who has read other articles that I have written- will know that the drawbacks of the treatment are difficult to ignore. Although around 10-15% of users experience regrowth, the medication has absolutely no effect for at least 1 in 3. The treatment also takes a long time to take effect- about 4 months- and requires indefinite use or the hair will begin to fall again. This combined with its significant and on going financial cost is enough to put off most potential users.

In my opinion, as a fellow sufferer of pre-mature baldness, an advanced non-surgical hair system, or wig- though, connecting the hair system with the wig, does not do it justice- is the best option. It provides practical, versatile, financially viable, and realistic hair cover for those of us who experience the loss of our hair.

Five Common Causes of Hair Loss (And What to Do About It)

Hair growth occurs in cycles and varies by individual. Most people lose 50-100 hair per day, and the hair that is lost is replaced by new hair growth. Typically, hair grows approximately ½ inch per month and the average individual has approximately 100,000 hairs in their scalp.

According to the American Academy of Dermatology, “The most common cause of hair loss is a medical condition called hereditary hair loss. About 80 million men and women in the United States have this type of hair loss. Other names for this type of hair loss are: male-pattern baldness, female-pattern baldness, or androgenetic alopecia.”

What is androgenetic alopecia and what can I do about it?

More commonly called referred to as “balding,” in men, men may experience this phenomenon as early as late teenage years or in their early 20s. Women may typically notice thinning of their hair due to hormonal changes in pregnancy and later on during menopause.

Both conditions are genetic and if there is a family history on either side of the family, your risk for this condition increases.

If you are concerned about your hair loss, see a dermatologist or specialist to rule out any underlying medical condition. If the hair loss is not due to a medical condition, you may seek cosmetic surgery or cosmetic enhancements to mitigate the appearance of balding or thinning.

Other causes of hair loss:

Cicatricial (scarring) alopecia

Cicatricial alopecia is caused by inflammation and damage to the hair follicle which prevents new hairs from growing. The cause of the inflammation is not known but this condition is inherent in a number of skin conditions, including lupus erythematosus or lichen planus.

Alopecia areata

Alopecia areata is an autoimmune disease of unknown origins. Since a family history of this condition increases your chances of developing it, doctors suspect that it may be hereditary and some people may be predisposed to develop it.

Luckily, your hair usually grows back, but you may lose and regrow it a number of times.

Telogen effluvium

Stories you hear about people losing their hair suddenly due to shock, grief or illness may be true. Telogen effluvium hair loss occurs after a severe physical or emotional trauma and causes the roots of the hair to go into a resting phase, while the affected hairs fall out. This is a temporary condition and new hair follicles will begin to grow within a month or two.

Causes of Telogen effluvium include: emotional distress, death of a loved one, physiological stress, such as a high fever, sudden or excessive weight loss, extreme diets, nutritional deficiencies, surgery, or metabolic disturbances.

Traction alopecia

Too many cornrows or tight braids that pull the hair too tightly may cause traction alopecia. If the hairstyle is relaxed before scarring or permanent damage to the root occurs, the hair will usually grow back.

Nizoral Shampoo Review for the Treatment of Traction Alopecia

Nizoral is a shampoo prescribed for seborrhoic dermatitis, dandruff and tinea versicolor (rash caused by fungus) but has been shown to have very positive effects on hair loss. Both men and women suffer from traction alopecia, and the use of Nizoral anti-dandruff shampoo shows promise in helping to treat both the symptoms and aid in the regrowth of lost hair.

Nizoral shampoo has ketoconazole, a synthetic antifungal preparation, which is used to treat dry scalp and dandruff. Preliminary studies suggest that the use of Nizoral shampoo, containing ketoconazole, beneficial in helping to increase the regrowth of lost hair.

It is thought to work by cleansing the scalp, removing pore blocking material and increasing circulation to the scalp. It reduces the effect of inflammation- caused by pulling the hair, and allows the hair follicle to receive essential nutrients that are needed for hair growth. Inflammation is also responsible for deactivating the hair follicle, which is why hair follicles afffected by traction alopecia remain in the dormant (telogen) phase.

Ketoconazole which is the active ingredient in Nizoral shampoo helps to reduce the levels of dihydrotestosterone (DHT) at the skin level. DHT when not removed from the scalp combines with other chemicals causing hair follicles to become permanently dormant.

Properly used a minimum of twice per week, Nizoral will keep the scalp clean and hair follicles active. While helping to increase the production of hair, the shampoo will also eliminate dandruff and relieve dry, irritated scalps. The shampoo also has a thickening effect on the hair. This is partly due to its effect on inflammation which ultimately results in the retention of more hair.

Nizoral Shampoo and its active ingredient, ketoconazole, make no open claims to regrow hair. Only that it has shown itself to be an effective addition to other treatments for traction alopecia hair loss and thinning hair.

Ketoconazole has few side effects other than occasional skin irritations to those with sensitive skin and those who attempt to overuse the product. It is always best to check with your doctor before starting any treatment and to test a small area of your scalp for a reaction prior to shampooing the first time. Nizoral can have a bit of a drying effect on hair and should be followed with a moisturing conditioner if you have dry hair. It is one of a few hair loss shampoos that can compliment other topical treatments for traction alopecia. If you have sensitive skin, a gentle stimulating herbal shampoo would probably be better suited to your scalp.

Hair growth occurs at the rate of approximately half an inch per month and so many people who begin treatment with Nizoral see a significant difference in as little as 30 to 60 days of use.

I Am Losing My Hair at a Young Age

Just after I had turned eighteen a close friend of mine looked at the top of my scalp and announced: “Dude, looks like you have a little bald spot!” But I was so young and it seemed so outrageous that I didn’t think a lot of it. That was until my early 20s when I discovered in a photograph that my widow’s peak was sneaking up higher on my forehead. The obvious widow’s peak is an apparent trait for the majority of the men in my family so again I ignored it assuming that was as far as it would go. The nearer I got to thirty the more obvious it became that my hairline was getting worse and that I was experiencing hair loss on my crown too. I was mortified. I was still a young man. Why was this happening? My self-esteem took a big hit and I was feeling a little disheartened.

It’s a horrible feeling when you realise that you are going bald particularly when you glance around your social group at all the full manes, you feel cheated and isolated. There is also the extra pressure on you from your peers because in modern culture a full head of hair is symbolic of youth and virility. It has you questioning yourself. Will you look undesirable to a new employer? Or even worse yet are you going to be dismissed by women?

There are lots of myths in relation to hair loss. Wearing caps is not going to make your hair fall out and neither will applying hair gel. It is actually natural to shed hair; believe it or not, the typical person will shed between 50 and 100 hairs a day. But for some these hairs are not always replaced. The most common cause of hair loss in males is the inherited condition androgenic alopecia which is more commonly referred to as male pattern baldness. Men with this problem have elevated levels of a hormone known as 5(alpha)-reductase, which transforms testosterone into dihydrotestosterone (DHT). DHT attacks hair follicles, gradually shrinking them which results in shorter, finer hair until eventually the hair follicle dies.

For those who have read this far and can relate then you have most likely come to grips with your loss of hair… but what can you do about it? You could try your best to hide it maybe with the good old comb over or in my instance the comb forward. Although that isn’t going to work forever and you will ultimately find yourself looking like Donald Trump.

A couple of commonly used hair loss remedies are Rogaine and Propecia. Rogaine is a solution that is applied directly to the scalp. Rogaine works to increase the size of shrunken hair follicles so they can produce lengthier, fuller hairs. Propecia is a capsule that works to slow down the generation of DHT (the hormone that we identified is liable for shrinking the hair follicles to begin with). The issue with both of these medications is that they contain finastercide which has been linked to erection problems and low sex drive. Another problem is that the minute you stop with such products your hair will go back to the original state.

Another alternative is laser treatment where a low-level laser is used to activate hair follicles and encourage hair growth. This is something which I have had personal experience with. I once gave an organization a significant amount of money for a plan made up entirely of the aforementioned drugs plus some laser hair sessions. There was very little improvement. Bear in mind that the effects will vary because naturally everyone is different; however, I surely could not see the justification of the multi-thousand dollar sale price.

The earlier remedies work on the philosophy that you detect your hair loss early. If it is too far gone in your case there are several aesthetic options available like a hair piece. These can be costly and hard to maintain. And despite looking realistic, all it takes is for somebody to run their fingers through your hair to understand that it isn’t real. You could also attempt hair transplants where healthy hair is harvested from the other regions of your head and relocated to the bald areas. It’s often a pricey or painful procedure and there is the risk of scarring.

The final alternative and this is one that I have been leaning towards lately is to just go bald gracefully. Shave your head. Look at a number of the guys out there making this look trendy. Michael Jordan, Vin Diesel and Bruce Willis just to name a few. True, it’s going to be daunting to make that initial leap, nevertheless you can find men out there with flawless hairlines that select this as a style because it looks hot and in many cases makes them look younger.

You need to realise that losing your hair is not the end of the universe although it is irritating because it is something you do not have any control over. Bare in mind you are not alone with research demonstrating that one in four men will encounter premature balding before they turn 30. It’s not your hair style that defines you. It’s how well you carry yourself.

Could I Have Something Internally Wrong With Me That Is Causing My Hair Loss?

I often hear from people who are having trouble determining the cause of their hair loss. They often can’t see where anything is wrong on the outside. I hear comments like: “my hair is shiny and healthy. My scalp seems fine. I don’t have any genetic or family history of thinning or baldness. And yet I am shedding hair more and more all of the time. Could there be some wrong internally that is causing my shedding?”

Before I answer, I have to tell you that I’m not a doctor. I highly encourage you to see one. I can tell you some internal issues that can cause hair loss, but should you suspect any of these issues, please see your doctor.

Yeast Issues: I have had many people with shedding tell me that they discovered that they had yeast overgrowth and once they got control over the situation, their hair loss improved. Also, sometimes the yeast will also be present on the scalp which can cause further problems. That’s why, anti dandruff shampoos can actually help to improve this situation for some.

Stress: Many specialists deny that stress can cause hair loss, but I have to admit that I have some doubt about this. I know too many people who can pinpoint nothing other than stress as the trigger for their hair fall. This is only my unscientific theory, but I’ve always wondered if the elevated cortisol associated with stress can aggravate or be a trigger for shedding. Regardless of my theories, it’s relatively easy to try to cut down on your stress. It’s noninvasive and it doesn’t cost anything, so it’s definitely worth a try.

Diet Or Supplements: Many times, if you drastically change your diet (like removing a lot of carbohydrates, turning vegetarian, or loading up on protein) you might bring on a form of hair loss known as telogen effluvium as the result. So, take a look at your lifestyle to see if you’ve made any changes to your diet that might be a culprit. I’ve also had people tell me that they believe dietary supplements or vitamins have caused hair loss for them, particularly women who take supplements which can affect or alter their hormones. Any change or addition to medications can cause shedding and many people don’t realize that supplements can bring out similar changes, especially when you start or stop them.

Medical Issues That Can Often Be Detected With Blood Work: There are many health issues that can cause hair loss. Low iron, vitamin deficiencies, thyroid issues, endocrine disorders, and autoimmune driven illnesses can cause changes in your hair. Your doctor can order blood work to see if any of these issues are likely based on your results. If so, you can then go to a specialist for treatment. But very often, blood work is the first step.

I hear from a lot of people who are discouraged that their doctor can not find the cause of their hair loss. I do understand this because you figure if you could determine the cause, you could then also determine the appropriate treatment and end this nightmare once and for all. However, it’s important to keep this in perspective. If your blood work shows no medical issues, then you can then move on and start looking at other triggers.

The Drug Propecia and Hair Loss

The drug propecia is a prescription hair loss medication designed mainly for men with mild to moderate hair loss. The effects of hair loss and propecia were studied in several clinical trials, and propecia was found to be better than a placebo.

The men in the studies, aged between 18 and 41, took propecia daily for a year. Some men took a placebo. Of the men who took the propecia, 86% either did not suffer further hair loss, or actually increased the amount of hair in the affected areas. Only 14% of men had continued hair loss.

The drug propecia has been found to be ineffective for women. This, combined with the potential danger of abnormalities to a male fetus, means that propecia is not prescribed for female pattern hair loss. Propecia has not been studied in older men, or men with complete baldness, and it has not been proved to work with a receding hairline. Propecia is not suitable for children, no doubt due to its negative effect on developing male genitals.

Generally, propecia is a very safe drug for hair loss. Most men taking it did not have any side effects, though some reported:

* erection difficulties
* reduced amount of semen
* less sexual desire

These were not permanent changes, and when those affected stopped taking propecia, their symptoms disappeared. Some men who reported these side effects were also able to continue taking propecia without the side effects continuing. The report I saw did not say whether the side effects just stopped, or if other treatment was undertaken to counteract them.

The drug propecia has only been studied on men for up to two years, and these men had no problems taking it for this period. However, based on research over a period of 32 years on men who are deficient on the enzyme that propecia suppresses, 5-alpha reductase, the mechanism by which propecia works seems to be quite safe for long term use.

Disadvantages of Taking Propecia

Propecia is not a cure for hair loss. Propecia works by interrupting the conversion process of testosterone to its metabolite, dihydrotestosterone (DHT for short). It does this by effecting the enzyme catalyst, 5-alpha reductase, that is involved in the conversion process. In male pattern hair loss, there is an excess of DHT in the part of the scalp where hair loss occurs. So, by reducing the amounts of DHT in the scalp, propecia effectively works to prevent new hair loss, and allows hair to regrow. However, to continue the benefits of propecia, you’ll need to take it for the rest of your life. Once you stop taking propecia, the DHT levels will rise again in the scalp, and hair loss will return to pre-propecia levels.

The Drug Propecia and Pregnancy

Women should be very careful not to handle propecia if they are pregnant, as it can affect the development of the sex organs in a male fetus. So, it would be wise not to touch any open packets, or broken tablets. If you must, use a glove. Unbroken tablets are safety coated, so the active ingredient of propecia, which is the potential problem, is not present on the outside of the tablet.

For men taking propecia, if your wife is pregnant, there is no risk to her unless she is exposed to the active ingredient from a broken tablet. She, or the baby, won’t be harmed when her partner is taking it.

However, given that in some men propecia affects the amount of semen produced, if you are trying to conceive this may pose a problem. This side effect does not affect all, or most, men. But check with your doctor if you think this may be a concern.


December 2012
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